By V. V. Didenko
The 1st complete therapy of strength move (ET) nucleic acid probes. Hands-on specialists completely describe the entire significant probes, either fluorescence resonance strength move (FRET)-based and non-FRET-based, and supply a whole set of suggestions to observe DNA and RNA reactions, together with hybridization, amplification, cleavage, folding, and institutions with proteins, different molecules, and steel ions. optimum layout ideas for custom designed ET probes are provided, in addition to ideas for distance selection in protein-DNA complexes and the detection of topological DNA changes, mutations, DNA breaks and unmarried nucleotide polymorphisms. Merging paintings on nanotechnology, and fluorescent probes, authors describe intimately the layout and alertness of ET-using molecular units, corresponding to biosensors, molecular machines, and good judgment gates for molecular scale computation.
Read Online or Download Fluorescent Energy Transfer Nucleic Acid Probes: Designs And Protocols (Methods in Molecular Biology Vol 335) PDF
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