By Leon E. Rosenberg M.D. (auth.), Aubrey Milunsky MB.B.Ch., D.Sc., F.R.C.P, D.C.H., George J. Annas J.D., M.P.H. (eds.)

It was once the easiest of instances, it was once the worst of occasions, it used to be the age of knowledge, it used to be the age of foolishness, it used to be the epoch of trust, it was once the epoch of incredulity, ... it was once the spring of wish, it used to be the wintry weather of melancholy. . . . -Charles Dickens, A story of 2 towns Dickens, in fact, didn't have the modern dilemmas of contemporary genetics in brain. certainly, we have to remind ourselves how brief the heritage of recent genetics relatively is. popularity that genetic qualities are carried by way of deoxyribonucleic acid (DNA) happened purely approximately forty years in the past. wisdom of the 3-dimensional constitution of DNA is barely approximately 30 years previous. the right kind variety of human chromosomes used to be now not deter­ mined until eventually the mid-1950s, and Down syndrome was once famous merely in 1959. It was once now not until eventually in 1968 that the precise situation of a gene was firm on an autosomal chromo­ a few, and the learn of genes, instead of their protein items, has been attainable for slightly a decade.

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