By Luis de Lecea (Editor), J. Gregor Sutcliffe (Editor)

The hypocretins (orexins) are a newly pointed out (1998) peptide relations constituted of peptides, hypocretin-1 and hypocretin-2. contemporary observations recommend an involvement of those peptides, situated essentially within the hypothalmus, within the law of behavioral nation. they're all for circadian rhythms, metabolism, hormone secretion, physique temperature, urge for food, cardiovascular features (e.g., blood pressure), and sleep abnormalities (e.g., narcolepsy and cataplexy).

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