By Jaekwon Lee, David Adle, Heejeong Kim (auth.), Markus J. Tamas, Enrico Martinoia (eds.)

One of the demanding situations confronted via each mobilephone in addition to through complete organisms is to take care of applicable concentrations of crucial nutrient metals whereas except nonessential poisonous metals. towards that finish, all organisms have constructed mechanisms for steel homeostasis and cleansing to keep up steel degrees inside of physiological limits. This ebook brings jointly present wisdom of the molecular foundation of steel homeostasis and detoxing in a number of eukaryotic version structures, together with yeasts, vegetation, and mammals. It specializes in the mobile structures controlling steel shipping, intracellular distribution, and immobilization in addition to on platforms regulating metal-dependent transcription. as well as environmental features (including phytoremediation), the booklet treats the pathophysiology of steel deficiency and overload with regards to disorder.

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