The untold tale of monoclonal antibodies—the molecular heroes of biotechnology that revolutionized the analysis and remedy of greater than fifty significant diseases

This e-book is the 1st to inform the extreme but unheralded historical past of monoclonal antibodies. also known as Mabs, they're strange to so much nonscientists, but those microscopic protein molecules are in all places, quietly shaping our lives and healthcare. stumbled on within the mid-1970s within the laboratory the place Watson and Crick had prior unveiled the constitution of DNA, Mabs have extensively replaced understandings of the pathways of affliction. they've got enabled speedier, more affordable, and extra exact medical diagnostic checking out on an unlimited scale. and so they have performed a basic position in pharmaceutical innovation, resulting in such advancements as recombinant interferon and insulin, and custom-made drug remedies akin to Herceptin. this day Mabs represent six of the world’s most sensible ten blockbuster medicines and make up a 3rd of recent brought treatments.
Lara V. Marks recounts the dangers and competition bold handful of people confronted whereas studying and constructing Mabs, and he or she addresses the similar clinical, clinical, technological, company, and social demanding situations that arose. She deals a saga of marketers whose patience and creativity finally replaced the healthcare panorama and taken untold aid to thousands of sufferers. in spite of this, as Marks exhibits, controversies over Mabs stay, and he or she examines present debates over the prices and effectiveness of those cutting edge drugs.

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