By Lucy W. Barrett, Sue Fletcher, Steve D. Wilton
There's now compelling proof that the complexity of upper organisms correlates with the relative quantity of non-coding RNA instead of the variety of protein-coding genes. formerly disregarded as “junk DNA”, it's the non-coding areas of the genome which are accountable for law, facilitating complicated temporal and spatial gene expression during the combinatorial impression of various mechanisms and interactions operating jointly to fine-tune gene expression. the key areas occupied with legislation of a selected gene are the five’ and three’ untranslated areas and introns. furthermore, pervasive transcription of advanced genomes produces various non-coding transcripts that engage with those areas and give a contribution to law. This publication discusses contemporary insights into the regulatory roles of the untranslated gene areas and non-coding RNAs within the keep watch over of complicated gene expression, in addition to the consequences of this when it comes to organism complexity and evolution.
Read or Download Untranslated Gene Regions and Other Non-coding Elements: Regulation of Eukaryotic Gene Expression (SpringerBriefs in Biochemistry and Molecular Biology) PDF
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